Development and evaluation of a hydrophilic matrix as a buccoadhesive system containing diclofenac sodium
نویسندگان
چکیده
منابع مشابه
Formulation and physicochemical characterization of buccoadhesive microspheres containing diclofenac sodium.
PURPOSE The present study involves preparation and evaluation of diclofenac buccal-mucoadhesive microparticles for prolongation of buccal residence time. METHODS The microparticles were prepared by modified double-emulsion dehydration method (O1/W/O2) using sodium carboxymethylcellulose (CMC-Na) as mucoadhesive polymer. Calcium chloride was used as a cross-linking agent. Buccal-mucoadhesive m...
متن کاملDesign and Evaluation of Diclofenac Sodium Megaloporous Matrix System Aimed for Colonic Drug Delivery
Megaloporous controlled release tablets of diclofenac sodium (DS) were prepared with two kinds of granules. One of them is the restraining-phase matrix granule (RMG) and it controls the release rate of the drug. The other one is the soluble housing-phase matrix granule (HMG) and controls liquid penetration into the system. Carnauba wax and Eudragit L 100 polymers were used to constitute th...
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design and evaluation of diclofenac sodium megaloporous matrix system aimed for colonic drug delivery
megaloporous controlled release tablets of diclofenac sodium (ds) were prepared with two kinds of granules. one of them is the restraining-phase matrix granule (rmg) and it controls the release rate of the drug. the other one is the soluble housing-phase matrix granule (hmg) and controls liquid penetration into the system. carnauba wax and eudragit l 100 polymers were used to constitute the res...
متن کاملDevelopment and Evaluation of Extended Release Ethylcellulose Based Matrix Tablet of Diclofenac Sodium
Objective: The present study involved the preparation of Diclofenac sodium extended release hydrophobic matrix tablets formulated from Ethylcellulose polymer following its different grades, Ethocel Standard Premium and Ethocel Standard FP Premium. Methods: The matrix tablets were prepared with wet granulation method. Lubricated blends were characterized for physical properties like loose bulk d...
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ژورنال
عنوان ژورنال: Brazilian Archives of Biology and Technology
سال: 2011
ISSN: 1516-8913
DOI: 10.1590/s1516-89132011000500006